Cellular and Molecular Biology PhD candidate in the Miller Lab at the University of Michigan. My thesis research focuses on alterations of stress response pathways in long-lived mice.
What do you get when you bring together a groundbreaking lesbian poet, a famous Zen philosopher, the founder of a prostitutes’ union and the inventor of the self-regulating filtered hot tub?
The answer: Druid Heights — a once-thriving Bay Area bohemia deep in the forest, now moldering despite the best efforts of its residents, a few hardy holdovers from the counterculture, to maintain it.
The graffiti artist who took Facebook stock instead of cash for painting the walls of the social network’s first headquarters made a smart bet. The shares owned by the artist, David Choe, are expected to be worth upward of $200 million when Facebook stock trades publicly later this year.
When the nation’s largest breast cancer advocacy organization considered in October cutting off most of its financial support to the nation’s largest abortion provider, the breast cancer group was hoping for a quiet end to an increasingly controversial partnership.
Instead, the organization, the Susan G. Komen for the Cure foundation, is now engulfed in a controversy that threatens to undermine one of the most successful advocacy campaigns. The foundation’s decision to eliminate most of its grants to Planned Parenthood for breast cancer screening caused a cascade of criticism from prominent women’s groups, politicians and public health advocates and a similarly strong outpouring of support from conservative women and religious groups that oppose abortion.
“This study provides an explanation for the clinical trial results demonstrating that in women with breast cancer antiangiogenic agents such as Avastin delay the time to tumor recurrence but do not affect patient survival. If our results apply to the clinic, it suggests that in order to be effective, these agents will need to be combined with cancer stem cell inhibitors, an approach now being explored in the laboratory,” says study author Max S. Wicha, M.D., director of the U-M Comprehensive Cancer Center.
The researchers treated mice with breast cancer using Avastin (bevacizumab) and Sutent (sunitinib), both of which work by stopping the growth and formation of blood vessels, a process called angiogenesis. The researchers found that tumors treated with these drugs developed more cancer stem cells, the small number of cells within a tumor that fuel a cancer’s growth and spread and that are often resistant to standard treatment. Both the number of cancer stem cells and the percentage of cancer stem cells that make up the tumor increased after being treated with each of these therapies.
The police arrived at Dotcom Mansion in Auckland on Friday morning in two helicopters. Mr. Dotcom, a 37-year-old with dual Finnish and German citizenship, retreated into a safe room, and the police had to cut their way in. He was eventually arrested with a firearm close by that the police said appeared to be a shortened shotgun.
“It was definitely not as simple as knocking at the front door,” said Grant Wormald, a detective inspector.
The police said they seized 6 million New Zealand dollars, or $4.8 million, in luxury vehicles, including a Rolls-Royce Phantom Drophead Coupe and a pink 1959 Cadillac. They also seized art and electronic equipment and froze 11 million dollars in cash in various accounts.
Set on an island off the coast of New England in the summer of 1965, MOONRISE KINGDOM tells the story of two twelve-year-olds who fall in love, make a secret pact, and run away together into the wilderness. As various authorities try to hunt them down, a violent storm is brewing off-shore — and the peaceful island community is turned upside down in more ways than anyone can handle.
Three crunchy taco supremes, no tomato, a cheesy gordita crunch and a Mexican pizza, no tomato. Every time.
From 1941 to 1978, this husband-wife powerhouse brought unique talents to their partnership. He was an architect by training; she was a painter and sculptor. Together their work helped shape the second half of the 20th century and remains culturally vital today. Narrated by James Franco, Charles & Ray Eames: The Architect and the Painter is the 25th anniversary season finale of American Masters.
Mike Daisey was a self-described “worshipper in the cult of Mac.” Then he saw some photos from a new iPhone, taken by workers at the factory where it was made. Mike wondered: Who makes all my crap? He traveled to China to find out.
Powerful stuff. This isn’t specific to Apple though. It’s a moral issue for all the major tech companies manufacturing in China.
One of my resolutions for this year is to keep better personal records. This is a great journaling app that syncs with Dropbox and has an iPhone version.
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