University of Michigan Cellular and Molecular Biology graduate student.

October 2007

Low buzz may give mice better bones and less fat [∞]

Dr. Rubin, director of the Center for Biotechnology at the State University of New York at Stony Brook, is reporting that in mice, a simple treatment that does not involve drugs appears to be directing cells to turn into bone instead of fat.

All he does is put mice on a platform that buzzes at such a low frequency that some people cannot even feel it. The mice stand there for 15 minutes a day, five days a week. Afterward, they have 27 percent less fat than mice that did not stand on the platform — and correspondingly more bone.

Greater Los Angeles [∞]

No matter what you do in L.A., your behavior is appropriate for the city. Los Angeles has no assumed correct mode of use. You can have fake breasts and drive a Ford Mustang – or you can grow a beard, weigh 300 pounds, and read Christian science fiction novels. Either way, you’re fine: that’s just how it works.

[...]

L.A. is the apocalypse: it’s you and a bunch of parking lots. No one’s going to save you; no one’s looking out for you. It’s the only city I know where that’s the explicit premise of living there – that’s the deal you make when you move to L.A.

The city, ironically, is emotionally authentic.

It says: no one loves you; you’re the least important person in the room; get over it.

What matters is what you do there.

Soap up! The 12 germiest places in your life [∞]
  1. Kitchen sink
  2. Airplane bathrooms
  3. A load of wet laundry
  4. Public drinking fountains
  5. Shopping cart handles
  6. ATM buttons
  7. Purses
  8. Playgrounds
  9. Health club workout equipment
  10. Bath tub
  11. Office phone
  12. Hotel room remote control
Huge pirate music site shut down [∞]

British and Dutch police have shut down a “widely-used” source of illegally-downloaded music. A flat on Teesside and several properties in Amsterdam were raided as part of an Interpol investigation into the members-only website OiNK.

The UK-run site has leaked 60 major pre-release albums this year alone, said the International Federation of the Phonographic Industry (IFPI).

A 24-year-old man from Middlesbrough was arrested on Tuesday morning.

There are a number of inaccuracies in the BBC report and press release issued by the IFPI. OiNK is not a pay site and does not specialize in distributing pre-release material. It is a free, by invitation only site that specializes in “secure” rips (i.e. with Exact Audio Copy) of hard to find, often out of print material.

Love reaches out to the Wizard for advice, history [∞]

WESTWOOD, Calif. — Ask John Wooden, UCLA’s living treasure, how he’s doing, and the legendary 97-year-old coach will respond with a still-quick wit and say, “Well, I’m here!”

He is. And, for however long he can continue to offer guidance or a living history of the UCLA program, Bruins freshman Kevin Love is going to listen.

J. K. Rowling at Carnegie Hall reveals Dumbledore is gay; Neville marries Hannah Abbott, and much more [∞]

Q: In the Goblet of Fire Dumbledore said his brother was prosecuted for practicing inappropriate charms [JKR buries her head, to laughter] on a goat; what were the inappropriate charms he was practicing on that goat?

JKR: How old are you?

Eight.

JKR: I think that he was trying to make a goat that was easy to keep clean [laughter], curly horns. That’s a joke that works on a couple of levels. I really like Aberforth and his goats. But you know Aberforth having this strange fondness for goats if you’ve read book seven, came in really useful to Harry, later on, because a goat, a stag, you know. If you’re a stupid Death Eater, what’s the difference. So, that is my answer to YOU.

[loud applause]

Did Dumbledore, who believed in the prevailing power of love, ever fall in love himself?

My truthful answer to you… I always thought of Dumbledore as gay. [ovation.] … Dumbledore fell in love with Grindelwald, and that that added to his horror when Grindelwald showed himself to be what he was. To an extent, do we say it excused Dumbledore a little more because falling in love can blind us to an extend, but he met someone as brilliant as he was, and rather like Bellatrix he was very drawn to this brilliant person, and horribly, terribly let down by him. Yeah, that’s how i always saw Dumbledore. In fact, recently I was in a script read through for the sixth film, and they had Dumbledore saying a line to Harry early in the script saying I knew a girl once, whose hair… [laughter]. I had to write a little note in the margin and slide it along to the scriptwriter, “Dumbledore’s gay!” [laughter] If I’d known it would make you so happy, I would have announced it years ago!

U2 beef up Joshua Tree for 20th anniversary reissues [∞]

In celebration, the Brian Eno/Daniel Lanois-produced modern classic will– according to Billboard.com– be re-released in four increasingly-elaborate ways: a single CD, a double-CD set, a double-CD/single-DVD box, and a double-vinyl package.

[...]

Billboard.com also creeped out onto a pretty shaky limb to add that “although details have yet to be announced, Joshua Tree demos, alternate versions, and B-sides from the period are expected to appear.” Whatever they’ve got, it’ll all hit shelves November 20 from UMe.

Astrophysicist replaces supercomputer with eight PlayStation 3s [∞]

Suffering from its exorbitant price point and a dearth of titles, Sony’s PlayStation 3 isn’t exactly the most popular gaming platform on the block. But while the console flounders in the commercial space, the PS3 may be finding a new calling in the realm of science and research.

Drug-resistant staph deaths may surpass AIDS toll [∞]

CHICAGO, Illinois (AP) — More than 90,000 Americans get potentially deadly infections each year from a drug-resistant staph “superbug,” the government reported Tuesday in its first overall estimate of invasive disease caused by the germ.

Deaths tied to these infections may exceed those caused by AIDS, said one public health expert commenting on the new study. The report shows just how far one form of the staph germ has spread beyond its traditional hospital setting.

The overall incidence rate was about 32 invasive infections per 100,000 people. That’s an “astounding” figure, said an editorial in Wednesday’s Journal of the American Medical Association, which published the study.


Radiohead’s In Rainbows experiment

Radiohead released their new studio album, In Rainbows, this morning as an MP3 download. The album has been thoroughly discussed in the media over the last week because the band decided to release the work independently without the help of a record label. The album is available for purchase in two formats from inrainbows.com: a digital download or a 2xCD, 2xLP discbox. The special edition discbox is priced at £40 (~U.S. $81 at the time of release). The digital download is available with no set price — you pay what you think the album is worth.

I think the “donationware” concept of the Radiohead album is an interesting idea. Personally, I am more inclinded to buy a group’s album if I know they are receiving money from the purchase. Radiohead is not the only band who is going to attempt to go it alone in the near future. A couple of days ago, Nine Inch Nails frontman Trent Reznor anounced on nin.com that he has not renewed his major label record contract and will attempt to go it alone like Radiohead. Rumors have been circulating around the Internet this week that Oasis and Jamiroquai will follow suit.

Digital distribution straight from the band is a great idea but I can already see a number of flaws in the model that need to be addressed. First, the album needs to be made available in a lossless format (i.e. FLAC) with no digital rights management attached. In Rainbows is available only as a low quality 160 kbps MP3 download. I am willing to pay for a lossless download but not an MP3. Until that’s available, I will stick with CD. The other problem is distribution. Radiohead opted to serve the MP3s straight from their site from 10 server mirrors. BitTorrent is a much better protocol for serving up a digital download to a large number of customers. Blizzard already uses BitTorrent to deliver World of Warcraft patches to its subscribers.